Knowing there is an innovative treatment available to keep my rosacea bumps and blemishes under control is really encouraging and exciting†
Let's clear up the facts
Combination treatment has the potential to improve outcomes. For this study, we added ORACEA® (doxycycline, USP) 40mg Capsules to SOOLANTRA® (ivermectin) Cream, 1% to measure efficacy and ensure the treatment approach aims for 'clear'.1 Clear is defined as IGA score of 0 according to the IGA (Investigator Global Assessment) scale, which is commonly used by dermatologists.
Both molecules have independent and cooperative effects on the inflammatory pathways of rosacea.
ORACEA® Capsules: Pivotal Study Information
The efficacy and safety of non antibiotic dose doxycycline (40-mg doxycycline monohydrate formulated as 30-mg immediate release and 10-mg delayed release beads) for the treatment of rosacea was evaluated in 537 subjects aged ≥ 18 years in identically designed, phase 3 trials.
ORACEA® Capsules are indicated for the treatment of only inflammatory lesions (papules and pustules) of rosacea in adult patients.
IGA = Investigator's Global Assessment.
ORACEA Capsules Significantly Reduced Inflammatory Lesions vs Placebo2,9
*Total inflammatory lesion count = papules + pulstules.
ORACEA Capsules Pivotal Studies: Safety10
In this clinical study, the most common treatment-related adverse events (:>4%) for ORACEA capsules were diarrhea, nausea, coated tongue, vomiting, and photosensitivity.9